7 Tygodni z Radical med efektyHair reduction, also called alopecia, might be a side effect of chemotherapy, targeted therapy, rays therapy, and stem cell transplants. The 1st clinical description of calvicie areata is attributed to Celsus (14 to 37 B. C. ), you as well as the designation alopecia areata through Sauvages. 2 Filon demonstrated the incorrectness of the hypothesis of yeast etiology as proposed by Willan and Gruby (1843). Later, Von Baresprung suggested the neurotrophic theory, and Jacquet elaborated the dystrophic theory, taking into consideration the disease to be caused by contagious focuses, particularly dental, a hypothesis today that has been totally discarded. Nowadays, alopecia areata is interpreted as an autoimmune disease with a genetic substrate.
In conclusion, the beneficial effect of T-cell subtype depletion on locks growth, the detection of autoantibodies, the ability to transfer alopecia areata from affected animals to nonaffected animals, and the induction of remission by grafting affected areas onto immunosuppressed animals are evidence on favor of an autoimmune phenomenon. Certain factors within the hair follicles, and possibly in the surrounding milieu, trigger an autoimmune effect. Some evidence suggests a melanocytic target in the curly hair follicle. Adding or subtracting immunologic factors profoundly changes the outcome of growth of hair.
Why does alopecia areata (AA) usually show a round alopecia laceracion rather than a sphenoid or a rectangular shape? The configu-ration and distribution of skin eruptions faithfully reflect the pathogenesis in the diseases. For example, patients with a creeping disease show a geradlinig eruption, perhaps somewhat equivalent with the movement of skin lesions in chrysalis migrans. Therefore, for comprehending the pathogenesis of AA, it is worthwhile to address the mechanism underlying its development within a round or an ovoid pattern.
Traction alopecia is usually because of extreme pulling or tension about hair shafts as a result of certain hair styles. It is definitely seen more often found in women, particularly those of East Indian and Afro-Caribbean origin. Hair loss depends on the way the hair is being pulled. Prolonged traction alopecia could end new locks follicles developing and business lead to permanent hair loss.
WHAT AREAS ARE AFFECTED?: The scalp is the usual area, but the beard in men, and eyelashes or eyebrows, might be affected alone or perhaps together with scalp hair loss. In the uncommon severe forms, body curly radical med ampułki dla mężczyzn hair may be lost mainly because well. The only various other structures affected are the nails - and persons with severe alopecia areata may show dull and rigid finger nails.